Madonna appeared in a pre-taped message from the candy shop she did all her interviews in NYC. She said that she thinks Ellen is a great dancer with a hot body and she thanked her for promoting her album.

Timberlake then came out and danced to "4 Minutes" with Ellen. Timberlake revealed that when the music for :"4 Minutes" was conceived, he wanted lyrics that were sexy and thematically more aligned with his last album. Madonna wanted something more serious. He told her that she can’t save the world in four minutes. Madonna decides to make the song "4 Minutes to Save the World."

Source: Drowned Madonna